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Publication: Zappia et al., 2023 - Osteomodulin downregulation is associated with osteoarthritis development
All Figures: Figures for Zappia et al., 2023

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Fig. 1

Localization of OMD in the murine knee joint. a Immunostaining of OMD (in brown) in the knee joint (medial tibial plateau) of KO, WT, and UP male mice at 4, 8, and 16 months. Scale bar = 100 µm. Zoom on specific areas from WT of 16 months. Scale bar = 25 µm for (b) and 50 µm for (c, d). Representative pictures with n = 3 for each group. b Uncalcified articular cartilage (ac) and calcified cartilage (cc), separated by the tidemark (td—dotted line); chondrocytes (arrowheads). c Subchondral bone (sb), growth plate (gp) and lining cells (lc). d Metaphysis of the tibia showing the cortical bone (cb), the outer medial tibial side and the inner tibial side facing the bone marrow are indicated with (*)

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