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Figure 5

ID: ZDB-IMAGE-200713-24
Publication: Coomer et al., 2020 - Her9/Hes4 is required for retinal photoreceptor development, maintenance, and survival
All Figures: Figures for Coomer et al., 2020

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Figure Caption

Figure 5

Cone outer segments are abnormal in her9 mutants. Immunohistochemistry with a red-green cone antibody (Zpr1) in her9^+/+ or ^+/− (A,A′) and her9^−/− (B,B′) retinal sections. Arrowheads indicate outer segments. (C–H) Immunohistochemistry with an antibody that labels rod and double cone outer segments (Zpr3) on retinal cryosections of TαC:GFP; her9^+/+ or ^+/− (C–E) or TαC:GFP; her9^−/− mutant (F–H) larvae. (I) Cone cell counts in her9^−/− mutant larvae and their WT and heterozygous siblings (# of Cones/100 µM). WT/Het = 10 embryos; Mut = 10 embryos; t-test (p < .0001). ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; GCL, ganglion cell layer; L, lens; ON, optic nerve; OS, outer segment; IS, inner segment. Scale bar = 100 µm.

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Phenotype details

Acknowledgments

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