u773 mutants show tectal apoptosis. (A,B) Lateral views of 2 dpf live wildtype (A) and u773 mutant (B) embryos. The arrowhead in (B) indicates dying tectal cells. (C,D) Transverse sections of the tecta of u773 mutants and siblings showing TUNEL labeled apoptotic cells (blue, arrowheads). (E,F) Lateral views of 5 dpf live wildtype (E) and u773 mutant (F) larvae. (G–H’) Dorsal views of brains of u773 mutants and siblings labeled with anti-acetylated tubulin (red) and SV2 antibodies showing organization of cells, processes and neuropil. (G’,H’) show magnified views of the boxes in (G) and (H). Note that in the u773 mutant, tubulin staining is aberrant. Scale bars: 200 μm.
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Full text @ Front Cell Dev Biol
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