IMAGE

Fig. 2.

ID: ZDB-IMAGE-200509-25
Publication: de Oliveira et al., 2020 - DnaJ-PKAc fusion induces liver inflammation in a zebrafish model of Fibrolamellar Carcinoma
All Figures: Figures for de Oliveira et al., 2020

Image

Figure Caption

Fig. 2.

Overexpression of Dnajb1a-Prkacaa(zfDnaJa-Pkaca)can induce liver masses at adult stages. (A) Representative maximum-intensity projections (MIPs) of 7 day post-fertilization (dpf) FLC larvae [Tg(fabp10a:dnajb1a-prkacaa)/Tg(fabp10a:egfp-l10a)] and control siblings [Tg(fabp10a:egfp-l10a)]. (B) Chi-square graphs showing percentages of fish with masses (8 months, control N=5, FLC N=8; 12 months, control N=5, FLC N=7). (C) Representative images of H&E staining of the livers of 12-month-old fish at 10× and 40× magnification. Yellow outlines delineate masses, white arrowheads indicate prominent nucleoli and black arrowheads indicate lipid vacuoles. Scale bars: 60 μm (10× magnification) and 10 μm (40× magnification). M, mass; N, normal tissue.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.