IMAGE

Fig. 6.

ID: ZDB-IMAGE-191230-640
Publication: Tomecka et al., 2019 - Clinical pathologies of bone fracture modelled in zebrafish
All Figures: Figures for Tomecka et al., 2019

Image

Figure Caption

Fig. 6.

Genetic ablation of osteoclasts reduces bone callus resorption. (A,B) TRAP staining of fractures in WT (A) and csf1ra^j4e1 mutants (B) at given time points following crush. (C) The area of TRAP staining was significantly reduced in the mutants at all time points (n=12). (D,E) Fluorescent images of WT (D) and csf1ra^j4e1 mutant (E) fractures stained with calcein. The time points following crush are given. (F) Relative callus width measurements at different time points for fractures of WT and csf1ra mutants at given time points (n=15). By 42 hpc, the mutants had significantly fewer remodelled calluses. *P<0.05, **P<0.01, ***P<0.001; ANOVA with Sidak post test. Scale bars: in B and D, 100 µm for A,B,D,E.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.