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Fig. 2.

ID: ZDB-IMAGE-191230-520
Publication: Ding et al., 2019 - Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish
All Figures: Figures for Ding et al., 2019

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Figure Caption

Fig. 2.

The bag3^e2/e2 mutant manifests a cardiac dysfunction phenotype. (A,B) Blood flow indices measured using a custom 30 MHz ultrasound probe. n=8-10, Student's t-test. (C) Examples of echocardiography images extracted from movies of beating hearts in WT controls and bag3^e2/e2 mutants at systole (upper panel) and diastole (lower panel). (D) Quantification of cardiac function indices measured by echocardiography in the bag3^e2/e2 mutant and WT control at 6 months. n=8, Student's t-test. (E-J) Cardiac pump function indices as measured by ex vivo heart pump function assay. n=12-13, Student's t-test. Data are mean±s.e.m.

Figure Data

Phenotype details

Acknowledgments

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