Gene
dlx1a
- ID
- ZDB-GENE-990415-48
- Name
- distal-less homeobox 1a
- Symbol
- dlx1a Nomenclature History
- Previous Names
-
- dlx1
- zgc:111939
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cartilage development and embryonic viscerocranium morphogenesis. Predicted to be active in nucleus. Is expressed in brain; pharyngeal arch; and ventricular zone. Orthologous to human DLX1 (distal-less homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 29 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu593 (11 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-dlx1a | (2) | |
| CRISPR2-dlx1a | (2) | |
| MO1-dlx1a | N/A | (3) |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Distal-less homeobox transcription factors | Helix-turn-helix motif | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q98875 | InterPro | 252 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(dlx1aIG:GFP) |
|
| 2 | (4) | |
| Tg(dlx1aURE2:GFP) |
|
| 2 | (5) |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-245G15 | ZFIN Curated Data | |
| Encodes | EST | eu593 | Thisse et al., 2005 | |
| Encodes | cDNA | MGC:111939 | ZFIN Curated Data |
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