Gene

ncam1a

ID
ZDB-GENE-990415-31
Name
neural cell adhesion molecule 1a
Symbol
ncam1a Nomenclature History
Previous Names
  • ncam1
  • ncam
  • zNCAM (1)
  • fj56g09
  • wu:fj56g09 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Acts upstream of or within posterior commissure morphogenesis. Predicted to be located in plasma membrane. Is expressed in several structures, including anterior neural keel; myotome; nervous system; optic vesicle; and pectoral fin. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; bipolar disorder; drug dependence; middle cerebral artery infarction; and nicotine dependence. Orthologous to human NCAM1 (neural cell adhesion molecule 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
27 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Langhauser et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la014026TgTransgenic insertionUnknownUnknownDNA
la021897TgTransgenic insertionUnknownUnknownDNA
sa1470Allele with one point mutationUnknownPremature StopENU
sa17923Allele with one point mutationUnknownPremature StopENU
sa23936Allele with one point mutationUnknownSplice SiteENU
sa37307Allele with one point mutationUnknownPremature StopENU
1 - 6 of 6
Show
Sequence Targeting Reagents
1 - 4 of 4
Show
Human Disease
Associated With ncam1a Human Ortholog
No data available
Associated With ncam1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR003961 Fibronectin type III
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
1 - 5 of 11 Show all
Domain Details Per Protein
Protein Additional Resources Length Cell Adhesion and Cytoskeletal Organization Fibronectin type III Fibronectin type III superfamily Immunoglobulin domain subtype Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype 2 Neural and epithelial cell adhesion domain-containing protein Neural cell adhesion
UniProtKB:A0A8M2B821 InterPro 989
UniProtKB:A0A8M2B824 InterPro 978
UniProtKB:A0A8M3B4M6 InterPro 994
UniProtKB:A0A8M2B827 InterPro 749
UniProtKB:A0A8M3ATS9 InterPro 1010
1 - 5 of 19 Show all
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 21
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ncam1a-201 (1) Ensembl 2,921 nt
mRNA ncam1a-202 (1) Ensembl 878 nt
mRNA ncam1a-206 (1) Ensembl 2,810 nt
mRNA ncam1a-207 (1) Ensembl 2,840 nt
ncRNA ncam1a-002 (1) Ensembl 903 nt
1 - 5 of 7 Show all
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanNCAM111
Conserved genome location (synteny) (2)
Amino acid sequence comparison (2)
MouseNcam19
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
Citations
1 - 10 of 34
Show