Gene
fbln7
- ID
- ZDB-GENE-170130-2
- Name
- fibulin 7
- Symbol
- fbln7 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in cell differentiation. Predicted to be located in extracellular region. Is expressed in mandibular arch skeleton; notochord; and pharyngeal arch.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Russell et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Complement Clr-like EGF domain | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Extracellular matrix structural protein | Fibulin, C-terminal Ig-like domain | Nephronectin domain-containing protein | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7FFU9 | InterPro | 442 | ||||||||||
| UniProtKB:A0A8M3AZF9 | InterPro | 396 | ||||||||||
| UniProtKB:A0A8M3BEV9 | InterPro | 400 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
No data available
No data available
- Zou, Q., Gang, K., Yang, Q., Liu, X., Tang, X., Lu, H., He, J., Luo, L. (2018) The CCCH-type zinc finger transcription factor Zc3h8 represses NF-κB-mediated inflammation in digestive organs in zebrafish. The Journal of biological chemistry. 293(31):11971-11983
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Russell, M.W., Raeker, M.O., Geisler, S.B., Thomas, P.E., Simmons, T.A., Bernat, J.A., Thorsson, T., Innis, J.W. (2014) Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations. Human molecular genetics. 23(16):4272-84
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