Gene
adgrg2a
- ID
- ZDB-GENE-140106-206
- Name
- adhesion G protein-coupled receptor G2a
- Symbol
- adgrg2a Nomenclature History
- Previous Names
-
- gpr64
- gpr64a
- zmp:0000001246 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within cell surface receptor signaling pathway. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; heart; integument; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in X-linked congenital bilateral absence of vas deferens. Orthologous to human ADGRG2 (adhesion G protein-coupled receptor G2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Harty et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
X-linked congenital bilateral absence of vas deferens | Alliance | Congenital bilateral absence of vas deferens, X-linked | 300985 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR000203 | GPS motif |
Conserved_site | IPR017983 | GPCR, family 2, secretin-like, conserved site |
Domain | IPR017452 | GPCR, rhodopsin-like, 7TM |
Domain | IPR017981 | GPCR, family 2-like, 7TM |
Family | IPR000832 | GPCR, family 2, secretin-like |
Homologous_superfamily | IPR046338 | GAIN domain superfamily |
Domain Details Per Protein
Protein | Additional Resources | Length | GAIN domain superfamily | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPCR, family 2, secretin-like, conserved site | GPCR, rhodopsin-like, 7TM | GPS motif |
---|---|---|---|---|---|---|---|---|
UniProtKB:E7F4F2 | InterPro | 947 | ||||||
UniProtKB:A0A8M2B9R8 | InterPro | 2289 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance