Gene
pgfb
- ID
- ZDB-GENE-131127-445
- Name
- placental growth factor b
- Symbol
- pgfb Nomenclature History
- Previous Names
-
- si:dkey-204k5.1
- zmp:0000000808
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor binding activity. Predicted to be involved in several processes, including cell surface receptor protein tyrosine kinase signaling pathway; positive regulation of chemotaxis; and sprouting angiogenesis. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; diabetic neuropathy; glioblastoma; myocardial infarction; and pancreatic endocrine carcinoma. Orthologous to human PGF (placental growth factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine-knot cytokine | PDGF/VEGF domain | Platelet-derived/Vascular endothelial growth factor |
|---|---|---|---|---|---|
| UniProtKB:A0A8M9PCW7 | InterPro | 158 | |||
| UniProtKB:X1WBL7 | InterPro | 164 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance