Gene

prkd2

ID
ZDB-GENE-131120-142
Name
protein kinase D2
Symbol
prkd2 Nomenclature History
Previous Names
  • bua
  • si:dkey-202l22.2
  • unm s411
  • unm_s411
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within endocardial cushion formation. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol. Is expressed in brain; gut; and heart. Orthologous to human PRKD2 (protein kinase D2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Just et al., 2011
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
s411Allele with one point mutationUnknownUnknownENU
zf454Allele with one point mutationUnknownMissenseENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-prkd2N/AJust et al., 2011
MO2-prkd2N/AGiardoglou et al., 2021
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Human Disease
Associated With prkd2 Human Ortholog
No data available
Associated With prkd2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
1 - 5 of 10 Show all
Domain Details Per Protein
Protein Additional Resources Length C1-like domain superfamily Diacylglycerol/phorbol-ester binding PH-like domain superfamily Pleckstrin homology domain Protein kinase, ATP binding site Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase C mu-related Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A0A8M9PLD4 InterPro 923
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 15
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prkd2-201 (1) Ensembl 6,355 nt
mRNA prkd2-202 (1) Ensembl 1,946 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-9F1ZFIN Curated Data
Contained inBACDKEY-202L22ZFIN Curated Data
EncodesESTfj10e04
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanPRKD219
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations