Gene

sytl2a

ID
ZDB-GENE-130723-2
Name
synaptotagmin-like 2a
Symbol
sytl2a Nomenclature History
Previous Names
  • slp2a (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable neurexin family protein binding activity. Acts upstream of or within blood vessel lumenization. Predicted to be located in membrane. Predicted to be active in exocytic vesicle and plasma membrane. Orthologous to human SYTL2 (synaptotagmin like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Francis et al., 2021
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Francis et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa8436Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa13534Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa27625Allele with one point mutationUnknownUnknownENU
Zebrafish International Resource Center (ZIRC) (order this)
1 - 3 of 3
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-sytl2a
    		Francis et al., 2021
    1 - 1 of 1
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    Human Disease
    Associated With sytl2a Human Ortholog
    No data available
    Associated With sytl2a Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR000008 C2 domain
    Domain IPR001565 Synaptotagmin
    Domain IPR010911 Rab-binding domain
    Domain IPR043567 Synaptotagmin-like 1-5, C2B domain
    Homologous_superfamily IPR035892 C2 domain superfamily
    1 - 5 of 5
    Domain Details Per Protein
    Protein Additional Resources Length C2 domain C2 domain superfamily Rab-binding domain Synaptotagmin Synaptotagmin-like 1-5, C2B domain
    UniProtKB:E7FB61 InterPro 909
    UniProtKB:A0A8M3B3F3 InterPro 1446
    UniProtKB:A0A8M3B3F7 InterPro 786
    UniProtKB:A0A8M9PU77 InterPro 1221
    UniProtKB:A0A8M3AWY6 InterPro 1281
    1 - 5 of 15 Show all
    Transcripts
    Genome Browsers
    No data available
    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Citations
    Your Input Welcome
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