Gene
snapc2
- ID
- ZDB-GENE-120328-2
- Name
- small nuclear RNA activating complex, polypeptide 2
- Symbol
- snapc2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II general transcription initiation factor activity. Acts upstream of or within intrahepatic bile duct development. Predicted to be active in nuclear body. Is expressed in brain and liver. Orthologous to human SNAPC2 (small nuclear RNA activating complex polypeptide 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Schaub et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Schaub et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-snapc2 | N/A | Schaub et al., 2012 |
| MO2-snapc2 | N/A | Schaub et al., 2012 |
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Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR021281 | Small nuclear RNA activating complex subunit 2 |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Small nuclear RNA activating complex subunit 2 |
|---|---|---|---|
| UniProtKB:E7F685 | InterPro | 413 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
snapc2-201
(1)
|
Ensembl | 1,833 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-196F2 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001923692 (1) | 1992 nt | ||
| Genomic | GenBank:BX470232 (1) | 194721 nt | ||
| Polypeptide | UniProtKB:E7F685 (1) | 413 aa |
- Comparative Orthology
- Alliance
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Ren, L., Tan, X.J., Xiong, Y.F., Xu, K., Zhou, Y., Zhong, H., Liu, Y., Hong, Y., Liu, S.J. (2014) Transcriptome analysis reveals positive selection on the divergent between topmouth culter and zebrafish. Gene. 552(2):265-71
- Schaub, M., Nussbaum, J., Verkade, H., Ober, E.A., Stainier, D.Y., and Sakaguchi, T.F. (2012) Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. Developmental Biology. 363(1):128-137
- Lo, J., Lee, S., Xu, M., Liu, F., Ruan, H., Eun, A., He, Y., Ma, W., Wang, W., Wen, Z., and Peng, J. (2003) 15,000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Genome research. 13(3):455-466
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