Gene
cxcl20
- ID
- ZDB-GENE-111004-2
- Name
- chemokine (C-X-C motif) ligand 20
- Symbol
- cxcl20 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable CXCR chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including cellular response to lipopolysaccharide; chemokine-mediated signaling pathway; and neutrophil chemotaxis. Predicted to act upstream of or within chemotaxis; defense response; and immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Chemokine beta/gamma/delta | Chemokine interleukin-8-like domain | Chemokine interleukin-8-like superfamily | CXC Chemokine domain |
---|---|---|---|---|---|---|
UniProtKB:A9ZPF6 | InterPro | 147 | ||||
UniProtKB:A0A8M3B9T3 | InterPro | 114 |
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- Genome Browsers
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
cxcl20-201
(1)
|
Ensembl | 2,083 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-210G19 |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001115055 (1) | 531 nt | ||
Genomic | GenBank:BX323596 (1) | 251428 nt | ||
Polypeptide | UniProtKB:A9ZPF6 (1) | 147 aa |
- Zhao, L., Wang, L.F., Wang, Y.C., Liu, A., Xiao, Q.W., Hu, M.C., Sun, M.Z., Hao, H.Y., Gao, Q., Zhao, X., Chen, D.Y. (2024) Deficiency of P2RY11 causes narcolepsy and attenuates the recruitment of neutrophils and macrophages in the inflammatory response in zebrafish. Cell biology and toxicology. 40:3636
- Casey, M.A., Hill, J.T., Hoshijima, K., Bryan, C.D., Gribble, S.L., Brown, J.T., Chien, C.B., Yost, H.J., Kwan, K.M. (2021) Shutdown corner, a large deletion mutant isolated from a haploid mutagenesis screen in zebrafish. G3 (Bethesda). 12(3):
- Porseryd, T., Reyhanian Caspillo, N., Volkova, K., Elabbas, L., Källman, T., Dinnétz, P., Olsson, P.E., Porsch-Hällström, I. (2018) Testis transcriptome alterations in zebrafish (Danio rerio) with reduced fertility due to developmental exposure to 17α-ethinyl estradiol. General and comparative endocrinology. 262:44-58
- Blaser, B.W., Moore, J.L., Hagedorn, E.J., Li, B., Riquelme, R., Lichtig, A., Yang, S., Zhou, Y., Tamplin, O.J., Binder, V., Zon, L.I. (2017) CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of experimental medicine. 214(4):1011
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Torraca, V., Cui, C., Boland, R., Bebelman, J.P., van der Sar, A.M., Smit, M.J., Siderius, M., Spaink, H.P., Meijer, A.H. (2015) The CXCR3/CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection. Disease models & mechanisms. 8(3):253-69
- Nguyen-Chi, M., Phan, Q.T., Gonzalez, C., Dubremetz, J.F., Levraud, J.P., Lutfalla, G. (2014) Transient infection of the zebrafish notochord with E. coli induces chronic inflammation. Disease models & mechanisms. 7:871-882
- Nomiyama, H., Osada, N., and Yoshie, O. (2013) Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history. Genes to cells : devoted to molecular & cellular mechanisms. 18(1):1-16
- van der Aa, L.M., Chadzinska, M., Derks, W., Scheer, M., Levraud, J.P., Boudinot, P., and Lidy Verburg-van Kemenade, B.M. (2012) Diversification of IFNγ-inducible CXCb chemokines in cyprinid fish. Developmental and comparative immunology. 38(2):243-253
- Rotman, J., van Gils, W., Butler, D., Spaink, H.P., and Meijer, A.H. (2011) Rapid screening of innate immune gene expression in zebrafish using reverse transcription - multiplex ligation-dependent probe amplification. BMC research notes. 4(1):196
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