ZFIN is now using GRCz12tu for Genomic Data
Gene
wnt7ab
- ID
- ZDB-GENE-100922-44
- Name
- wingless-type MMTV integration site family, member 7Ab
- Symbol
- wnt7ab Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cytokine activity and frizzled binding activity. Predicted to be involved in several processes, including canonical Wnt signaling pathway; neuron differentiation; and positive regulation of JNK cascade. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in hindbrain and hindbrain neural keel.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Beretta et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fuhrmann syndrome | Alliance | Fuhrmann syndrome | 228930 |
| Schinzel type phocomelia | Alliance | Ulna and fibula, absence of, with severe limb deficiency | 276820 |
| ?Santos syndrome | 613005 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Wnt | Wnt-7 protein | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|---|
| UniProtKB:E7FBM9 | InterPro |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
wnt7ab-201
(1)
|
Ensembl | 1,053 nt | ||
| mRNA |
wnt7ab-202
(1)
|
Ensembl | 1,594 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers