Gene

tox3

ID
ZDB-GENE-090312-209
Name
TOX high mobility group box family member 3
Symbol
tox3 Nomenclature History
Previous Names
  • si:dkey-117i6.1 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable chromatin DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in rhombomere 3; rhombomere 5; and telencephalon. Orthologous to human TOX3 (TOX high mobility group box family member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa9897Allele with one point mutationUnknownSplice SiteENU
sa15483Allele with one point mutationUnknownPremature StopENU
sa34124Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-tox3N/AHuang et al., 2013
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Human Disease
Associated With tox3 Human Ortholog
No data available
Associated With tox3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009071 High mobility group box domain
Family IPR051365 TOX high mobility group box domain-containing protein
Homologous_superfamily IPR036910 High mobility group box domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length High mobility group box domain High mobility group box domain superfamily TOX high mobility group box domain-containing protein
UniProtKB:A0A8M9PS17 InterPro 158
UniProtKB:E7FAU5 InterPro 587
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 7
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tox3-201 (1) Ensembl 4,118 nt
mRNA tox3-202 (1) Ensembl 2,661 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-117I6ZFIN Curated Data
Contained inBACDKEY-181O16ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanTOX316
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseTox38
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 8 of 8
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