Gene
zeb2b
- ID
- ZDB-GENE-080717-1
- Name
- zinc finger E-box binding homeobox 2b
- Symbol
- zeb2b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including convergent extension; mesenchymal cell differentiation; and regionalization. Predicted to be located in chromosome and nucleoplasm. Is expressed in several structures, including digestive system; nervous system; presumptive mesoderm; tail bud; and vagal neural crest. Human ortholog(s) of this gene implicated in Hirschsprung's disease and Mowat-Wilson syndrome. Orthologous to human ZEB2 (zinc finger E-box binding homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Mowat-Wilson syndrome | Alliance | Mowat-Wilson syndrome | 235730 |
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Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Drought induced 19 protein type, zinc-binding domain | Homedomain-like superfamily | Homeodomain | Zinc finger C2H2 superfamily | Zinc finger C2H2-type | Zinc finger E-box-binding homeobox |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QAF0 | InterPro | 1219 | ||||||
| UniProtKB:B0LVF0 | InterPro | 1219 |
1 - 2 of 2
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available