Gene
hspb9
- ID
- ZDB-GENE-080214-6
- Name
- heat shock protein, alpha-crystallin-related, 9
- Symbol
- hspb9 Nomenclature History
- Previous Names
-
- hspb14 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be active in cytoplasm and nucleus. Is expressed in notochord and somite. Orthologous to human HSPB9 (heat shock protein family B (small) member 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Alpha crystallin/Hsp20 domain | Alpha crystallin/Small heat shock protein, animal type | HSP20-like chaperone |
---|---|---|---|---|---|
UniProtKB:A5JV82 | InterPro | 204 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001114705 (1) | 667 nt | ||
Genomic | GenBank:CT574577 (1) | 108746 nt | ||
Polypeptide | UniProtKB:A5JV82 (1) | 204 aa |
Species | Symbol | Chromosome | Accession # | Evidence |
---|---|---|---|---|
Human | HSPB9 | 17 | Amino acid sequence comparison (1) |
- Li, S., Li, H., Bennewitz, K., Poschet, G., Buettner, M., Hausser, I., Szendroedi, J., Nawroth, P.P., Kroll, J. (2025) Combined loss of glyoxalase 1 and aldehyde dehydrogenase 3a1 amplifies dicarbonyl stress, impairs proteasome activity resulting in hyperglycemia and activated retinal angiogenesis. Metabolism: clinical and experimental. :156149156149
- Lu, X., Zhang, L., Lin, G.M., Lu, J.G., Cui, Z.B. (2024) Analysis of Differential Gene Expression under Acute Lead or Mercury Exposure in Larval Zebrafish Using RNA-Seq. Animals : an open access journal from MDPI. 14(19):
- Huang, S., Zhang, H., Chen, W., Su, N., Yuan, C., Zhang, J., Xiang, S., Hu, X. (2023) CRISPR/Cas9-Mediated Knockout of tnfaip1 in Zebrafish Plays a Role in Early Development. Genes. 14(5):
- Shields, J.N., Hales, E.C., Ranspach, L.E., Luo, X., Orr, S., Runft, D., Dombkowski, A., Neely, M.N., Matherly, L.H., Taub, J., Baker, T.R., Thummel, R. (2019) Exposure of Larval Zebrafish to the Insecticide Propoxur Induced Developmental Delays that Correlate with Behavioral Abnormalities and Altered Expression of hspb9 and hspb11. Toxics. 7(4):
- Zhang, R., Wang, X., Zhang, X., Zhang, J., Zhang, X., Shi, X., Crump, D., Letcher, R.J., Giesy, J.P., Liu, C. (2018) Down-Regulation of hspb9 and hspb11 Contributes to Wavy Notochord in Zebrafish Embryos Following Exposure to Polychlorinated Diphenylsulfides. Environmental science & technology. 52(21):12829-12840
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Marvin, M., O'Rourke, D., Kurihara, T., Juliano, C.E., Harrison, K.L., and Hutson, L.D. (2008) Developmental expression patterns of the zebrafish small heat shock proteins. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(2):454-463
- Elicker, K.S., and Hutson, L.D. (2007) Genome-wide analysis and expression profiling of the small heat shock proteins in zebrafish. Gene. 403(1-2):60-69
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