Gene

amer2

ID
ZDB-GENE-070719-5
Name
APC membrane recruitment protein 2
Symbol
amer2 Nomenclature History
Previous Names
  • fam123a (1)
  • zgc:165647
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to enable beta-catenin binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in ectoderm development and negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adipose tissue; blood; central nervous system; liver; and pleuroperitoneal region. Orthologous to human AMER2 (APC membrane recruitment protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Große et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
li18Allele with one deletionUnknownUnknownTALEN
li19Allele with one deletionUnknownUnknownTALEN
sa37898Allele with one point mutationUnknownPremature StopENU
1 - 3 of 3
Show
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
TALEN1-amer2Große et al., 2019
1 - 1 of 1
Show
Human Disease
Associated With amer2 Human Ortholog
No data available
Associated With amer2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR019003 APC membrane recruitment protein
1 - 1 of 1
Domain Details Per Protein
Protein Additional Resources Length APC membrane recruitment protein
UniProtKB:F1QGH6 InterPro 654
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 24
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA amer2-201 (1) Ensembl 3,424 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-11P10ZFIN Curated Data
EncodescDNAMGC:165647ZFIN Curated Data
1 - 2 of 2
Show
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanAMER213
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseAmer214
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 3 of 3
Show