Gene
pmaip1
- ID
- ZDB-GENE-070119-3
- Name
- phorbol-12-myristate-13-acetate-induced protein 1
- Symbol
- pmaip1 Nomenclature History
- Previous Names
-
- Noxa (1)
- zgc:162379
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Acts upstream of or within positive regulation of apoptotic process. Is expressed in several structures, including blastomere; head; pleuroperitoneal region; scale; and yolk syncytial layer. Orthologous to human PMAIP1 (phorbol-12-myristate-13-acetate-induced protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Zhong et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR024140 | Phorbol-12-myristate-13-acetate-induced protein 1 |
1 - 1 of 1
Domain Details Per Protein
| Protein | Additional Resources | Length | Phorbol-12-myristate-13-acetate-induced protein 1 |
|---|---|---|---|
| UniProtKB:Q0GKC8 | InterPro | 45 |
1 - 1 of 1
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pmaip1-201
(1)
|
Ensembl | 1,171 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
- Liu, Z.X., Zou, T.T., Liu, H.H., Jia, H.B., Zhang, X.Q. (2025) Knockout of the fcsk gene in zebrafish causes neurodevelopmental defects. Zoological research. 46:313324313-324
- Kong, S., Xiao, Y., Chen, L., Jin, Y., Qiao, R., Xu, K., Xu, L., Wang, H. (2024) Apigenin attenuates cisplatin-induced hair cell damage in the zebrafish lateral line. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 194:115099
- Wang, Z., Wang, C., Zhai, Y., Bai, Y., Wang, H., Rong, X. (2024) Loss of Brcc3 in Zebrafish Embryos Increases Their Susceptibility to DNA Damage Stress. International Journal of Molecular Sciences. 25(22):
- Wu, X., Peng, X., Zhang, Y., Peng, W., Lu, X., Deng, T., Nie, G. (2024) New application of ombuoside in protecting auditory cells from cisplatin-induced ototoxicity via the apoptosis pathway. Heliyon. 10:e39166e39166
- Xie, B., Liang, J., Jiang, J., Zeng, T., Liu, L., Xie, D., Zhu, G., Xiong, L., Zhang, K., Liu, D., Gong, J., Chen, X., Lai, R., Xie, H. (2024) Zebrafish myo7aa affects congenital hearing by regulating Rho-GTPase signaling. Frontiers in molecular neuroscience. 17:14051091405109
- Chen, J., Baxi, K., Lipsitt, A.E., Hensch, N.R., Wang, L., Sreenivas, P., Modi, P., Zhao, X.R., Baudin, A., Robledo, D.G., Bandyopadhyay, A., Sugalski, A., Challa, A.K., Kurmashev, D., Gilbert, A.R., Tomlinson, G.E., Houghton, P., Chen, Y., Hayes, M.N., Chen, E.Y., Libich, D.S., Ignatius, M.S. (2023) Defining function of wild-type and three patient specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma. eLIFE. 12:
- Morgan, K.J., Doggett, K., Geng, F., Mieruszynski, S., Whitehead, L., Smith, K.A., Hogan, B.M., Simons, C., Baillie, G.J., Molania, R., Papenfuss, A.T., Hall, T.E., Ober, E.A., Stainier, D.Y.R., Gong, Z., Heath, J.K. (2023) ahctf1 and kras mutations combine to amplify oncogenic stress and restrict liver overgrowth in a zebrafish model of hepatocellular carcinoma. eLIFE. 12:
- Ding, Q., Hao, Q., Zhang, Q., Yang, Y., Olsen, R.E., Ringø, E., Ran, C., Zhang, Z., Zhou, Z. (2022) Excess DHA Induces Liver Injury via Lipid Peroxidation and Gut Microbiota-Derived Lipopolysaccharide in Zebrafish. Frontiers in nutrition. 9:870343
- Wang, C., Zhang, X., Wang, X., Zhai, Y., Li, M., Pan, J., Bai, Y., Rong, X., Zhou, J. (2022) Genetic deletion of hspa8 leads to selective tissue malformations in zebrafish embryonic development. Journal of Cell Science. 135(21):
- Zasu, A., Hishima, F., Thauvin, M., Yoneyama, Y., Kitani, Y., Hakuno, F., Volovitch, M., Takahashi, S.I., Vriz, S., Rampon, C., Kamei, H. (2022) NADPH-Oxidase Derived Hydrogen Peroxide and Irs2b Facilitate Re-oxygenation-Induced Catch-Up Growth in Zebrafish Embryo. Frontiers in endocrinology. 13:929668
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