Gene
arhgap32a
- ID
- ZDB-GENE-060503-918
- Name
- Rho GTPase activating protein 32a
- Symbol
- arhgap32a Nomenclature History
- Previous Names
-
- fa92e11
- fi73a01
- si:dkey-287f10.3
- wu:fa92e11
- wu:fi73a01
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in small GTPase-mediated signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm and endomembrane system. Predicted to be active in several cellular components, including Golgi apparatus; actin cytoskeleton; and nuclear lumen. Is expressed in telencephalon. Orthologous to human ARHGAP32 (Rho GTPase activating protein 32).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Diotel et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa12990 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa17301 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa28431 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa32026 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa35856 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa35857 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | PX Domain-Containing Rho GAP | PX domain superfamily | Rho GTPase-activating protein domain | Rho GTPase activation protein | SH3 domain | SH3-like domain superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9PC13 | InterPro | 124 | ||||||
UniProtKB:F1RDK4 | InterPro | 1676 | ||||||
UniProtKB:A0A8M9PIK1 | InterPro | 1478 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
arhgap32a-201
(1)
|
Ensembl | 7,048 nt | ||
mRNA |
arhgap32a-202
(1)
|
Ensembl | 222 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-1O11 | ZFIN Curated Data | |
Contained in | BAC | DKEY-287F10 | ZFIN Curated Data | |
Encodes | EST | fa92e11 | ||
Encodes | EST | fi73a01 |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_685829 (1) | 6110 nt | ||
Genomic | GenBank:AL845312 (1) | 174959 nt | ||
Polypeptide | UniProtKB:F1RDK4 (1) | 1676 aa |
- Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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