Gene
rims3
- ID
- ZDB-GENE-060503-788
- Name
- regulating synaptic membrane exocytosis 3
- Symbol
- rims3 Nomenclature History
- Previous Names
-
- si:ch211-239d6.1
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of presynaptic active zone. Predicted to be involved in regulation of synaptic vesicle exocytosis; synaptic vesicle docking; and synaptic vesicle priming. Predicted to act upstream of or within exocytosis. Predicted to be located in membrane and synapse. Predicted to be active in presynaptic active zone cytoplasmic component and presynaptic membrane. Orthologous to human RIMS3 (regulating synaptic membrane exocytosis 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
la013425Tg | Transgenic insertion | Unknown | Unknown | DNA | |
sa1224 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa36842 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa36843 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 4 of 4
Show
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | C2 domain | C2 domain superfamily | Rim-like |
---|---|---|---|---|---|
UniProtKB:A0A8M1NF70 | InterPro | 305 | |||
UniProtKB:A5PMY1 | InterPro | 319 |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-239D6 | ZFIN Curated Data | |
Contained in | BAC | DKEY-119M17 | ZFIN Curated Data |
1 - 2 of 2
Show
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001100009 (1) | 960 nt | ||
Genomic | GenBank:BX927077 (1) | 239130 nt | ||
Polypeptide | UniProtKB:A5PMY1 (1) | 319 aa |
Species | Symbol | Chromosome | Accession # | Evidence |
---|---|---|---|---|
Human | RIMS3 | 1 | Amino acid sequence comparison (1) |
- Shankar, P., Garcia, G.R., LaDu, J.K., Sullivan, C.M., Dunham, C.L., Goodale, B.C., Waters, K.M., Stanisheuski, S., Maier, C.S., Thunga, P., Reif, D.M., Tanguay, R.L. (2022) The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior. Toxicological sciences : an official journal of the Society of Toxicology. 187(2):325-344
- Sun, C., Galicia, C., Stenkamp, D.L. (2018) Transcripts within rod photoreceptors of the Zebrafish retina. BMC Genomics. 19:127
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Sundström, G., Dreborg, S., and Larhammar, D. (2010) Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. PLoS One. 5(5):e10512
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
1 - 6 of 6
Show