Gene
loxl1
- ID
- ZDB-GENE-060503-693
- Name
- lysyl oxidase-like 1
- Symbol
- loxl1 Nomenclature History
- Previous Names
-
- si:ch211-238c15.1
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable protein-lysine 6-oxidase activity. Acts upstream of or within notochord development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in hypochord and notochord. Human ortholog(s) of this gene implicated in Kuhnt-Junius degeneration; exfoliation syndrome; and primary open angle glaucoma. Orthologous to human LOXL1 (lysyl oxidase like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Gansner et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| exfoliation syndrome | Alliance | {Exfoliation syndrome, susceptibility to} | 177650 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Lysyl oxidase | Lysyl oxidase, conserved site | Lysyl oxidase-like protein |
|---|---|---|---|---|---|
| UniProtKB:Q2PS19 | InterPro | 526 |
Interactions and Pathways
No data available
Plasmids
No data available