Gene
slc2a15b
- ID
- ZDB-GENE-050508-1
- Name
- solute carrier family 2 member 15b
- Symbol
- slc2a15b Nomenclature History
- Previous Names
-
- zgc:113085
- zglut9b (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable D-glucose transmembrane transporter activity. Predicted to be involved in D-glucose import and dehydroascorbic acid transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including heart; integument; kidney; liver; and xanthoblast.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7157428 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Glucose transporter GLUT | Major facilitator, sugar transporter-like | Major facilitator superfamily domain | MFS transporter superfamily | Sugar/inositol transporter | Sugar transporter, conserved site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q52KK7 | InterPro | 522 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc2a15b-201
(1)
|
Ensembl | 1,909 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Et(slc2a15b:EGFP) |
|
| 1 | Sander et al., 2017 |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-147L18 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7157428 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:113085 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192847 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001020494 (1) | 1950 nt | ||
| Genomic | GenBank:CT573247 (1) | 104960 nt | ||
| Polypeptide | UniProtKB:Q52KK7 (1) | 522 aa |
No data available
- Xiao, Y., Miao, Z., Sun, J., Xing, W., Wei, Y., Bai, J., Ye, H., Si, Y., Cai, L. (2023) Allisartan Isoproxil Promotes Uric Acid Excretion by Interacting with Intestinal Urate Transporters in Hyperuricemic Zebrafish (Danio rerio). Bulletin of experimental biology and medicine. 175(5):638-643
- Lencer, E., Prekeris, R., Artinger, K.B. (2021) Single-cell RNA analysis identifies pre-migratory neural crest cells expressing markers of differentiated derivatives. eLIFE. 10:
- Pohl, J., Golovko, O., Carlsson, G., Örn, S., Schmitz, M., Ahi, E.P. (2021) Gene co-expression network analysis reveals mechanisms underlying ozone-induced carbamazepine toxicity in zebrafish (Danio rerio) embryos. Chemosphere. 276:130282
- Lewis, V.M., Saunders, L.M., Larson, T.A., Bain, E.J., Sturiale, S.L., Gur, D., Chowdhury, S., Flynn, J.D., Allen, M.C., Deheyn, D.D., Lee, J.C., Simon, J.A., Lippincott-Schwartz, J., Raible, D.W., Parichy, D.M. (2019) Fate plasticity and reprogramming in genetically distinct populations of Danio leucophores. Proceedings of the National Academy of Sciences of the United States of America. 116(24):11806-11811
- Sun, Y., Zhang, B., Luo, L., Shi, D.L., Wang, H., Cui, Z., Huang, H., Cao, Y., Shu, X., Zhang, W., Zhou, J., Li, Y., Du, J., Zhao, Q., Chen, J., Zhong, H., Zhong, T.P., Li, L., Xiong, J.W., Peng, J., Xiao, W., Zhang, J., Yao, J., Yin, Z., Mo, X., Peng, G., Zhu, J., Chen, Y., Zhou, Y., Liu, D., Pan, W., Zhang, Y., Ruan, H., Liu, F., Zhu, Z., Meng, A., ZAKOC Consortium (2019) Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome research. 30(1):118-26
- Sander, V., Patke, S., Lee, J.Y., Chang, Y.T., Davidson, A.J. (2017) The Vital Dye CDr10b Labels the Zebrafish Mid-Intestine and Lumen. Molecules. 22(3)
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Kimura, T., Nagao, Y., Hashimoto, H., Yamamoto-Shiraishi, Y., Yamamoto, S., Yabe, T., Takada, S., Kinoshita, M., Kuroiwa, A., and Naruse, K. (2014) Leucophores are similar to xanthophores in their specification and differentiation processes in medaka. Proceedings of the National Academy of Sciences of the United States of America. 111(20):7343-7348
- Tseng, Y.C., Chen, R.D., Lee, J.R., Liu, S.T., Lee, S.J., and Hwang, P.P. (2009) Specific Expression and Regulation of Glucose Transporters in Zebrafish Ionocytes. American journal of physiology. Regulatory, integrative and comparative physiology. 297(2):R275-R290
- Wotton, K.R., Weierud, F.K., Dietrich, S., and Lewis, K.E. (2008) Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates. BMC Evolutionary Biology. 8:171
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