Gene
zc3h18
- ID
- ZDB-GENE-050419-13
- Name
- zinc finger CCCH-type containing 18
- Symbol
- zc3h18 Nomenclature History
- Previous Names
-
- si:ch211-218c6.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to be located in nucleus. Orthologous to human ZC3H18 (zinc finger CCCH-type containing 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la020290Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa23270 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa36616 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | E3 ligase, CCCH-type zinc finger | Zinc finger, CCCH-type | Zinc finger CCCH-type domain-containing protein |
|---|---|---|---|---|---|
| UniProtKB:A0A0R4IEF8 | InterPro | 1134 | |||
| UniProtKB:Q1LUE5 | InterPro | 1148 | |||
| UniProtKB:A0A8M2B620 | InterPro | 1135 | |||
| UniProtKB:A0AB32T8F2 | InterPro | 1133 | |||
| UniProtKB:A0AB32TC19 | InterPro | 1134 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zc3h18-201
(1)
|
Ensembl | 3,447 nt | ||
| mRNA |
zc3h18-202
(1)
|
Ensembl | 1,457 nt | ||
| mRNA |
zc3h18-203
(1)
|
Ensembl | 4,433 nt | ||
| mRNA |
zc3h18-204
(1)
|
Ensembl | 7,101 nt | ||
| mRNA |
zc3h18-205
(1)
|
Ensembl | 6,990 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-187I23 | ZFIN Curated Data | |
| Contained in | BAC | CH211-218C6 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001044339 (1) | 4433 nt | ||
| Genomic | GenBank:AL935038 (1) | 139077 nt | ||
| Polypeptide | UniProtKB:Q1LUE5 (1) | 1148 aa |
- Vejnar, C.E., Abdelmessih, M., Takacs, C., Yartseva, V., Oikonomou, P., Christiano, R., Stoeckius, M., Lau, S., Lee, M., Beaudoin, J.D., Musaev, D., Darwich-Codore, H., Walther, T., Tavazoie, S., Cifuentes, D., Giraldez, A. (2019) Genome wide analysis of 3'-UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish. Genome research. 29(7):1100-1114
- Beaudoin, J.D., Novoa, E.M., Vejnar, C.E., Yartseva, V., Takacs, C.M., Kellis, M., Giraldez, A.J. (2018) Analyses of mRNA structure dynamics identify embryonic gene regulatory programs. Nature structural & molecular biology. 25(8):677-686
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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