Gene

gadd45bb

ID
ZDB-GENE-050223-1
Name
growth arrest and DNA-damage-inducible, beta b
Symbol
gadd45bb Nomenclature History
Previous Names
  • gadd45b1 (1)
  • gadd45bl
  • zgc:112453
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Acts upstream of or within somitogenesis. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including margin; mesoderm; musculature system; solid lens vesicle; and yolk syncytial layer. Orthologous to human GADD45B (growth arrest and DNA damage inducible beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la023646TgTransgenic insertionUnknownUnknownDNA
sa31288Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-gadd45bbN/AKawahara et al., 2005
MO2-gadd45bbN/AChen et al., 2016
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Human Disease
Associated With gadd45bb Human Ortholog
No data available
Associated With gadd45bb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004038 Ribosomal protein eL8/eL30/eS12/Gadd45
Family IPR024824 Growth arrest and DNA damage-inducible protein GADD45
Homologous_superfamily IPR029064 Ribosomal protein eL30-like superfamily
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Domain Details Per Protein
Protein Additional Resources Length Growth arrest and DNA damage-inducible protein GADD45 Ribosomal protein eL30-like superfamily Ribosomal protein eL8/eL30/eS12/Gadd45
UniProtKB:Q5NU21 InterPro 158
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 2
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA gadd45bb-201 (1) Ensembl 1,390 nt
ncRNA gadd45bb-002 (1) Ensembl 783 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(UAS:gadd45bb,myl7:EGFP)
  • Danio rerio
1 (2)
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Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-193B15ZFIN Curated Data
EncodesESTeu542Thisse et al., 2005
EncodescDNAMGC:112453ZFIN Curated Data
EncodescDNAMGC:192984ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanGADD45B19
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseGadd45b10
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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