Gene
rdh5
- ID
- ZDB-GENE-050208-411
- Name
- retinol dehydrogenase 5 (11-cis/9-cis)
- Symbol
- rdh5 Nomenclature History
- Previous Names
-
- hsd17b9 (1)
- im:6901729
- si:dkey-102c8.5
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity. Acts upstream of or within eye photoreceptor cell differentiation; retina development in camera-type eye; and vitamin A biosynthetic process. Predicted to be located in membrane. Is expressed in several structures, including gut; heart; pineal complex; skeletal muscle cell; and visual system. Human ortholog(s) of this gene implicated in fundus albipunctatus and night blindness. Orthologous to human RDH5 (retinol dehydrogenase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6901729 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| fundus albipunctatus | Alliance | Fundus albipunctatus | 136880 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | NAD(P)-binding domain superfamily | Short-chain dehydrogenase/reductase, conserved site | Short-chain dehydrogenase/reductase SDR |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2BLL9 | InterPro | 326 | |||
| UniProtKB:Q4V8Y1 | InterPro | 328 | |||
| UniProtKB:F1RCW4 | InterPro | 328 |
Interactions and Pathways
No data available
Plasmids
No data available