Gene

ndrg2

ID
ZDB-GENE-041212-15
Name
NDRG family member 2
Symbol
ndrg2 Nomenclature History
Previous Names
  • im:6909381 (1)
  • si:dkey-88n24.1
  • zgc:101847 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to be involved in signal transduction. Predicted to act upstream of or within Wnt signaling pathway; cell differentiation; and nervous system development. Predicted to be active in cytoplasm. Is expressed in several structures, including intermediate cell mass of mesoderm; nervous system; optic cup; pectoral fin bud; and yolk. Orthologous to human NDRG2 (NDRG family member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Wang et al., 2023
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa18676Allele with one point mutationUnknownSplice SiteENU
zf4080unknownExon 2UnknownCRISPR
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-ndrg2Wang et al., 2023
MO1-ndrg2N/AWang et al., 2023
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Human Disease
Associated With ndrg2 Human Ortholog
No data available
Associated With ndrg2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004142 NDRG
Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
1 - 2 of 2
Domain Details Per Protein
Protein Additional Resources Length Alpha/Beta hydrolase fold NDRG
UniProtKB:Q5PR98 InterPro 368
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 7
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ndrg2-201 (1) Ensembl 7,368 nt
mRNA ndrg2-202 (1) Ensembl 1,843 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-353H16ZFIN Curated Data
Contained inBACDKEY-88N24ZFIN Curated Data
EncodesESTIMAGE:6909381Thisse et al., 2004
EncodescDNAMGC:101847ZFIN Curated Data
1 - 4 of 4
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanNDRG214
Amino acid sequence comparison (1)
MouseNdrg214
Amino acid sequence comparison (1)
Citations
1 - 10 of 10
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