Gene
akr1b1.2
- ID
- ZDB-GENE-041210-132
- Name
- aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2
- Symbol
- akr1b1.2 Nomenclature History
- Previous Names
-
- si:dkey-180p18.9
- zgc:153855
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable aldose reductase (NADPH) activity. Predicted to act upstream of or within lipid metabolic process. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in arteriosclerosis; cataract; diabetic neuropathy; diabetic retinopathy; and type 2 diabetes mellitus. Orthologous to several human genes including AKR1B1 (aldo-keto reductase family 1 member B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138896 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Aldo-keto reductase | Aldo/keto reductase, conserved site | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q1JPZ2 | InterPro | 316 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
akr1b1 (1 of many)-201
(1)
|
Ensembl | 1,592 nt |
Interactions and Pathways
No data available
Plasmids
No data available