Gene
anxa3b
- ID
- ZDB-GENE-041114-128
- Name
- annexin A3b
- Symbol
- anxa3b Nomenclature History
- Previous Names
-
- zgc:92888
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable calcium-dependent phospholipid binding activity and phosphatidylserine binding activity. Predicted to be active in several cellular components, including nucleus; plasma membrane; and vesicle membrane. Is expressed in dorsal aorta. Orthologous to human ANXA3 (annexin A3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la017643Tg | Transgenic insertion | Unknown | Unknown | DNA |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Annexin | Annexin A3 | Annexin repeat | Annexin repeat, conserved site | Annexin superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A8E5E5 | InterPro | 340 | |||||
| UniProtKB:Q5U369 | InterPro | 340 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
anxa3b-201
(1)
|
Ensembl | 1,669 nt | ||
| ncRNA |
anxa3b-002
(1)
|
Ensembl | 760 nt | ||
| ncRNA |
anxa3b-003
(1)
|
Ensembl | 810 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-47M8 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:92888 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:173763 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:174328 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:191554 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001007302 (1) | 1681 nt | ||
| Genomic | GenBank:BX571668 (1) | 242710 nt | ||
| Polypeptide | UniProtKB:A8E5E5 (1) | 340 aa |
- Rostad, K.O., Trognitz, T., Frøyset, A.K., Bifulco, E., Fladmark, K.E. (2024) Accelerated Sarcopenia Phenotype in the DJ-1/Park7-Knockout Zebrafish. Antioxidants (Basel, Switzerland). 13(12):
- Han, H., Jiang, G., Kumari, R., Silic, M.R., Owens, J.L., Hu, C.D., Mittal, S.K., Zhang, G.J. (2021) Loss of smarcad1a accelerates tumorigenesis of malignant peripheral nerve sheath tumors in zebrafish. Genes, chromosomes & cancer. 60(11):743-761
- Giffen, K.P., Liu, H., Kramer, K.L., He, D.Z. (2019) Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Frontiers in neuroscience. 13:1117
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Saxena, S., Purushothaman, S., Meghah, V., Bhatti, B., Poruri, A., Meena Lakshmi, M.G., Sarath Babu, N., Murthy, C.L., Mandal, K.K., Kumar, A., Idris, M.M. (2016) Role of Annexin gene and its regulation during zebrafish caudal fin regeneration. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 24(3):551-9
- Meadows, S.M., Cleaver, O. (2015) Annexin A3 Regulates Early Blood Vessel Formation. PLoS One. 10:e0132580
- Singh, S.K., Sethi, S., Aravamudhan, S., Krüger, M., and Grabher, C. (2013) Proteome mapping of adult zebrafish marrow neutrophils reveals partial cross species conservation to human peripheral neutrophils. PLoS One. 8(9):e73998
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Macqueen, D.J., and Johnston, I.A. (2008) Evolution of follistatin in teleosts revealed through phylogenetic, genomic and expression analyses. Development genes and evolution. 218(1):1-14
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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