Gene
lrrcc1
- ID
- ZDB-GENE-041111-207
- Name
- leucine rich repeat and coiled-coil centrosomal protein 1
- Symbol
- lrrcc1 Nomenclature History
- Previous Names
-
- im:7144254
- si:ch211-106h4.13
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to be located in centriole. Predicted to be active in centrosome and cytoplasm. Is expressed in head. Orthologous to human LRRCC1 (leucine rich repeat and coiled-coil centrosomal protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Li et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa19791 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa19792 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa32950 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa39854 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Leucine-rich repeat | Leucine-rich repeat domain superfamily |
|---|---|---|---|---|
| UniProtKB:F1R597 | InterPro | 997 | ||
| UniProtKB:A0AB32T9X8 | InterPro | 838 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lrrcc1-201
(1)
|
Ensembl | 4,060 nt | ||
| mRNA |
lrrcc1-202
(1)
|
Ensembl | 1,984 nt | ||
| mRNA |
lrrcc1-203
(1)
|
Ensembl | 3,872 nt | ||
| mRNA |
lrrcc1-204
(1)
|
Ensembl | 4,664 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-106H4 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7144254 | Thisse et al., 2004 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_685289 (1) | 3384 nt | ||
| Genomic | GenBank:CR293515 (1) | 192891 nt | ||
| Polypeptide | UniProtKB:F1R597 (1) | 997 aa |
- Choi, M.K., Cook, A., Mungikar, K., Eachus, H., Tochwin, A., Linke, M., Gerber, S., Ryu, S. (2024) Exposure to elevated glucocorticoid during development primes altered transcriptional responses to acute stress in adulthood. iScience. 27:110160110160
- Li, J., Liu, F., Lv, Y., Sun, K., Zhao, Y., Reilly, J., Zhang, Y., Tu, J., Yu, S., Liu, X., Qin, Y., Huang, Y., Gao, P., Jia, D., Chen, X., Han, Y., Shu, X., Luo, D., Tang, Z., Liu, M. (2021) Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing. Nucleic acids research. 49(4):2027-2043
- Feng, S., Wang, S., Wang, Y., Yang, Q., Wang, D., Li, H. (2018) Identification and expression of carbonic anhydrase 2, myosin regulatory light chain 2 and selenium-binding protein 1 in zebrafish Danio rerio: Implication for age-related biomarkers. Gene expression patterns : GEP. 29:47-58
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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