Gene
ccl38.1
- ID
- ZDB-GENE-041014-320
- Name
- chemokine (C-C motif) ligand 38, duplicate 1
- Symbol
- ccl38.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable chemokine activity. Predicted to act upstream of or within chemotaxis and immune response. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including IgA vasculitis; aggressive periodontitis; autoimmune disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Orthologous to several human genes including CCL13 (C-C motif chemokine ligand 13); CCL14 (C-C motif chemokine ligand 14); and CCL18 (C-C motif chemokine ligand 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CC chemokine, conserved site | Chemokine beta/gamma/delta | Chemokine interleukin-8-like domain | Chemokine interleukin-8-like superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:X1WEY1 | InterPro | |||||
| UniProtKB:A9ZPE8 | InterPro | 106 | ||||
| UniProtKB:A0AB32TC92 | InterPro | 136 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ccl38.1-201
(1)
|
Ensembl | 670 nt | ||
| mRNA |
ccl38.1-202
(1)
|
Ensembl | 321 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-217M5 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001082896 (1) | 369 nt | ||
| Genomic | GenBank:AL845306 (2) | 186675 nt | ||
| Polypeptide | UniProtKB:A0AB32TC92 (1) | 136 aa |
No data available
- Jerison, E.R., Quake, S.R. (2020) Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo. eLIFE. 9:
- Page, D.J., Thuret, R., Venkatraman, L., Takahashi, T., Bentley, K., Herbert, S.P. (2019) Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis. Cell Reports. 27:3139-3151.e5
- Zhou, T., Li, N., Jin, Y., Zeng, Q., Prabowo, W., Liu, Y., Tian, C., Bao, L., Liu, S., Yuan, Z., Fu, Q., Gao, S., Gao, D., Dunham, R., Shubin, N.H., Liu, Z. (2018) Chemokine C-C motif ligand 33 is a key regulator of teleost fish barbel development. Proceedings of the National Academy of Sciences of the United States of America. 115(22):E5018-E5027
- Blaser, B.W., Moore, J.L., Hagedorn, E.J., Li, B., Riquelme, R., Lichtig, A., Yang, S., Zhou, Y., Tamplin, O.J., Binder, V., Zon, L.I. (2017) CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of experimental medicine. 214(4):1011
- Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
- Wu, C.C., Tsai, T.H., Chang, C., Lee, T.T., Lin, C., Cheng, I.H., Sun, M.C., Chuang, Y.J., Chen, B.S. (2014) On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio. PLoS One. 9:e97902
- Nomiyama, H., Osada, N., and Yoshie, O. (2013) Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history. Genes to cells : devoted to molecular & cellular mechanisms. 18(1):1-16
- Nomiyama, H., Hieshima, K., Osada, N., Kato-Unoki, Y., Otsuka-Ono, K., Takegawa, S., Izawa, T., Yoshizawa, A., Kikuchi, Y., Tanase, S., Miura, R., Kusuda, J., Nakao, M., and Yoshie, O. (2008) Extensive Expansion and Diversification of the Chemokine Gene Family in Zebrafish: Identification of a Novel Chemokine Subfamily CX. BMC Genomics. 9(1):222
- Devries, M.E., Kelvin, A.A., Xu, L., Ran, L., Robinson, J., and Kelvin, D.J. (2006) Defining the origins and evolution of the chemokine/chemokine receptor system. Journal of immunology (Baltimore, Md. : 1950). 176(1):401-415
- Peatman, E., and Liu, Z. (2006) CC chemokines in zebrafish: Evidence for extensive intrachromosomal gene duplications. Genomics. 88(3):381-385
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