Gene
ccl38a.5
- ID
- ZDB-GENE-041014-167
- Name
- chemokine (C-C motif) ligand 38, duplicate 5
- Symbol
- ccl38a.5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable chemokine activity. Predicted to act upstream of or within chemotaxis and immune response. Predicted to be located in extracellular space.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-ccl38a.5 | Wright et al., 2024 | |
| CRISPR2-ccl38a.5 | Wright et al., 2024 | |
| CRISPR3-ccl38a.5 | Wright et al., 2024 | |
| CRISPR4-ccl38a.5 | Wright et al., 2024 | |
| MO1-ccl38a.5 | N/A | Cambier et al., 2014 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CC chemokine, conserved site | Chemokine beta/gamma/delta | Chemokine interleukin-8-like domain | Chemokine interleukin-8-like superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q5TYQ0 | InterPro | 103 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ccl38a.5-201
(1)
|
Ensembl | 532 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEYP-59A8 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001030173 (1) | 532 nt | ||
| Genomic | GenBank:BX957287 (1) | 154419 nt | ||
| Polypeptide | UniProtKB:Q5TYQ0 (1) | 103 aa |
No data available
- Wright, K., Han, D.J., Song, R., de Silva, K., Plain, K.M., Purdie, A.C., Shepherd, A., Chin, M., Hortle, E., Wong, J.J., Britton, W.J., Oehlers, S.H. (2024) Zebrafish tsc1 and cxcl12a increase susceptibility to mycobacterial infection. Life science alliance. 7(4):
- Ge, X., Huang, S., Ren, C., Zhao, L. (2023) Taurocholic Acid and Glycocholic Acid Inhibit Inflammation and Activate Farnesoid X Receptor Expression in LPS-Stimulated Zebrafish and Macrophages. Molecules. 28(5):
- Ollewagen, T., Benecke, R.M., Smith, C. (2023) High species homology potentiates quantitative inflammation profiling in zebrafish using immunofluorescence. Heliyon. 10:e23635e23635
- Chen, X.K., Kwan, J.S., Wong, G.T., Yi, Z.N., Ma, A.C., Chang, R.C. (2022) Leukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio). Experimental & molecular medicine. 54(7):973-987
- He, S., Fan, H., Sun, B., Yang, M., Liu, H., Yang, J., Liu, J., Luo, S., Chen, Z., Zhou, J., Xia, L., Zhang, S., Yan, B. (2022) Tibetan medicine salidroside improves host anti-mycobacterial response by boosting inflammatory cytokine production in zebrafish. Frontiers in pharmacology. 13:936295
- Luo, K., Ogawa, M., Ayer, A., Britton, W.J., Stocker, R., Kikuchi, K., Oehlers, S.H. (2022) Zebrafish Heme Oxygenase 1a Is Necessary for Normal Development and Macrophage Migration. Zebrafish. 19(1):7-17
- He, M., Halima, M., Xie, Y., Schaaf, M.J.M., Meijer, A.H., Wang, M. (2020) Ginsenoside Rg1 Acts as a Selective Glucocorticoid Receptor Agonist with Anti-Inflammatory Action without Affecting Tissue Regeneration in Zebrafish Larvae. Cells. 9(5):
- Sommer, F., Ortiz Zacarı As, N.V., Heitman, L.H., Meijer, A.H. (2020) Inhibition of macrophage migration in zebrafish larvae demonstrates in vivo efficacy of human CCR2 inhibitors. Developmental and comparative immunology. 116:103932
- Yang, B., Maddison, L.A., Zaborska, K.E., Dai, C., Yin, L., Tang, Z., Zang, L., Jacobson, D.A., Powers, A.C., Chen, W. (2020) RIPK3-mediated inflammation is a conserved β cell response to ER stress. Science advances. 6(51):
- Archambault, L.S., Trzilova, D., Gonia, S., Gale, C., Wheeler, R.T. (2019) Intravital Imaging Reveals Divergent Cytokine and Cellular Immune Responses to Candida albicans and Candida parapsilosis. mBio. 10(3):
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