Gene

cited2

ID
ZDB-GENE-041010-141
Name
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
Symbol
cited2 Nomenclature History
Previous Names
  • zgc:103418
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable transcription coactivator activity. Predicted to act upstream of or within cell differentiation and regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including brain; immature eye; lens; optic primordium; and pharyngeal arch. Used to study congenital heart disease. Human ortholog(s) of this gene implicated in atrial heart septal defect 8 and ventricular septal defect. Orthologous to human CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Santos et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-cited2N/ASantos et al., 2019
MO2-cited2N/ASantos et al., 2019
1 - 2 of 2
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Human Disease
Associated With cited2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
atrial heart septal defect 8 Alliance Atrial septal defect 8 614433
ventricular septal defect Alliance Ventricular septal defect 2 614431
1 - 2 of 2
Associated With cited2 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR007576 CITED
1 - 1 of 1
Domain Details Per Protein
Protein Additional Resources Length CITED
UniProtKB:Q5XJD6 InterPro 222
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 20
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cited2-201 (1) Ensembl 2,345 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-34F16ZFIN Curated Data
EncodescDNAMGC:103418ZFIN Curated Data
EncodescDNAMGC:193027ZFIN Curated Data
1 - 3 of 3
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanCITED26
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseCited210
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 10 of 17
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