Gene

rbx1

ID
ZDB-GENE-041008-106
Name
ring-box 1, E3 ubiquitin protein ligase
Symbol
rbx1 Nomenclature History
Previous Names
  • im:7137515
  • zgc:136444 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable cullin family protein binding activity and ubiquitin protein ligase activity. Acts upstream of or within ventricular trabecula myocardium morphogenesis. Predicted to be located in cytoplasm. Predicted to be part of cullin-RING ubiquitin ligase complex. Predicted to be active in nucleus. Is expressed in female organism. Orthologous to human RBX1 (ring-box 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Sarvari et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
bns148Allele with one deletionExon 3UnknownTALEN
1 - 1 of 1
Show
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-rbx1N/AHuang et al., 2013
TALEN1-rbx1Sarvari et al., 2021
1 - 2 of 2
Show
Human Disease
Associated With rbx1 Human Ortholog
No data available
Associated With rbx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Domain IPR024766 Zinc finger, RING-H2-type
Family IPR051031 RING-box E3 Ubiquitin Ligase
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
1 - 4 of 4
Domain Details Per Protein
Protein Additional Resources Length RING-box E3 Ubiquitin Ligase Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-H2-type Zinc finger, RING-type
UniProtKB:A4FUL3 InterPro 108
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 3
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rbx1-201 (1) Ensembl 548 nt
mRNA rbx1-202 (1) Ensembl 474 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(fli1:rbx1-2A-Tomato)
  • Danio rerio
1Sarvari et al., 2021
Tg(myl7:rbx1-2A-Tomato)
  • Danio rerio
1Sarvari et al., 2021
1 - 2 of 2
Show
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-256M1ZFIN Curated Data
EncodesESTIMAGE:7137515Thisse et al., 2004
EncodescDNAMGC:136444ZFIN Curated Data
1 - 3 of 3
Show
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRBX122
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseRbx115
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 9 of 9
Show