ZFIN is now using GRCz12tu for Genomic Data
Gene
spout1
- ID
- ZDB-GENE-040912-53
- Name
- SPOUT domain containing methyltransferase 1
- Symbol
- spout1 Nomenclature History
- Previous Names
-
- cb90 (1)
- sb:cb90
- zgc:101748
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable miRNA binding activity. Predicted to be involved in maintenance of centrosome location and miRNA processing. Predicted to act upstream of or within methylation. Predicted to be active in kinetochore; mitotic spindle; and spindle pole centrosome. Is expressed in several structures, including blood; central nervous system; neural tube; optic vesicle; and tail bud. Orthologous to human SPOUT1 (SPOUT domain containing methyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7160913 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with poor growth, seizures, and brain abnormalities | 621154 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/beta knot methyltransferases | Nucleic acid-binding, OB-fold | Putative RNA methyltransferase C9orf114-like | tRNA (guanine-N1-)-methyltransferase, N-terminal |
|---|---|---|---|---|---|---|
| UniProtKB:Q66ID3 | InterPro | 381 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spout1-201
(1)
|
Ensembl | 1,396 nt | ||
| mRNA |
spout1-203
(1)
|
Ensembl | 722 nt | ||
| mRNA |
spout1-204
(1)
|
Ensembl | 918 nt | ||
| ncRNA |
zgc:101748-004
(1)
|
Ensembl | 810 nt |
Interactions and Pathways
No data available
Plasmids
No data available