Gene

homer1b

ID
ZDB-GENE-040801-44
Name
homer scaffold protein 1b
Symbol
homer1b Nomenclature History
Previous Names
  • homer1
  • zgc:100854
  • zgc:92844
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled glutamate receptor binding activity. Acts upstream of or within intracellular calcium ion homeostasis and muscle structure development. Predicted to be located in cytosol and dendritic spine. Predicted to be active in several cellular components, including dendrite; plasma membrane; and postsynaptic density. Is expressed in several structures, including basal plate midbrain region; cardiovascular system; central nervous system; musculature system; and retina. Orthologous to human HOMER1 (homer scaffold protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Lin et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
nv1165Allele with one deletionUnknownUnknownCRISPR
1 - 1 of 1
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-homer1bN/ALin et al., 2013
1 - 1 of 1
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Human Disease
Associated With homer1b Human Ortholog
No data available
Associated With homer1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000697 WH1/EVH1 domain
Domain IPR044100 Homer, EVH1 domain
Family IPR045027 Homer family
Homologous_superfamily IPR011993 PH-like domain superfamily
1 - 4 of 4
Domain Details Per Protein
Protein Additional Resources Length Homer, EVH1 domain Homer family PH-like domain superfamily WH1/EVH1 domain
UniProtKB:A0A8M9Q8D4 InterPro 231
UniProtKB:B8JIC5 InterPro 398
UniProtKB:A0A0R4INT7 InterPro 360
UniProtKB:A0A8M2B3L5 InterPro 193
1 - 4 of 4
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA homer1b-202 (1) Ensembl 2,450 nt
mRNA homer1b-203 (1) Ensembl 2,349 nt
ncRNA ottdart00000061888 (1) Ensembl 1,463 nt
1 - 3 of 3
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-262A22ZFIN Curated Data
Contained inBACRP71-26J15ZFIN Curated Data
EncodesESTIMAGE:7140241Thisse et al., 2004
EncodescDNAMGC:92844ZFIN Curated Data
EncodescDNAMGC:100854ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanHOMER15
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseHomer113
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 10 of 10
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