Gene

rac3a

ID
ZDB-GENE-040718-256
Name
Rac family small GTPase 3a
Symbol
rac3a Nomenclature History
Previous Names
  • rac3 (1)
  • wu:fb95b01
  • zgc:100831
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Rac protein signal transduction; cytoskeleton organization; and motor neuron axon guidance. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be active in several cellular components, including cytoplasmic vesicle; cytoskeleton; and neuron projection. Is expressed in blastomere; hatching gland; nervous system; somite; and trigeminal placode. Orthologous to human RAC3 (Rac family small GTPase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la015193TgTransgenic insertionUnknownUnknownDNA
1 - 1 of 1
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-rac3a
    Doan et al., 2025
    1 - 1 of 1
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    Human Disease
    Associated With rac3a Human Ortholog
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies 618577
    1 - 1 of 1
    Associated With rac3a Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR005225 Small GTP-binding domain
    Family IPR001806 Small GTPase
    Family IPR003578 Small GTPase Rho
    Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
    1 - 4 of 4
    Domain Details Per Protein
    Protein Additional Resources Length P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTPase Rho Small GTP-binding domain
    UniProtKB:Q6DGB7 InterPro 192
    1 - 1 of 1
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 3
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA rac3a-201 (1) Ensembl 1,849 nt
    1 - 1 of 1
    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH211-117C2ZFIN Curated Data
    Contained inBACCH211-234H8ZFIN Curated Data
    EncodesESTfb95b01Rauch et al., 2003
    EncodesESTIMAGE:7138689Thisse et al., 2004
    EncodescDNAMGC:100831ZFIN Curated Data
    1 - 5 of 5
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanRAC317
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    MouseRac311
    Amino acid sequence comparison (1)
    Citations
    1 - 10 of 12
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