Gene

wasf2

ID
ZDB-GENE-040426-865
Name
WASP family member 2
Symbol
wasf2 Nomenclature History
Previous Names
  • zgc:56010 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable Arp2/3 complex binding activity and protein kinase A regulatory subunit binding activity. Acts upstream of or within heart development. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of SCAR complex. Predicted to be active in lamellipodium. Orthologous to human WASF2 (WASP family member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Edwards et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa36914Allele with one point mutationUnknownPremature StopENU
sw108Allele with one delinsExon 7UnknownCRISPR
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-wasf2
    Edwards et al., 2020
    CRISPR2-wasf2Luo et al., 2022
    1 - 2 of 2
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    Human Disease
    Associated With wasf2 Human Ortholog
    No data available
    Associated With wasf2 Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR003124 WH2 domain
    Family IPR028288 SCAR/WAVE family
    1 - 2 of 2
    Domain Details Per Protein
    Protein Additional Resources Length SCAR/WAVE family WH2 domain
    UniProtKB:A0A8M1P4I3 InterPro 486
    1 - 1 of 1
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 19
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA wasf2-201 (1) Ensembl 3,321 nt
    1 - 1 of 1
    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH211-199G17ZFIN Curated Data
    EncodescDNAMGC:56010ZFIN Curated Data
    EncodescDNAMGC:192007ZFIN Curated Data
    1 - 3 of 3
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanWASF21
    Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    MouseWasf24
    Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Citations
    1 - 6 of 6
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