Gene
rpsa
- ID
- ZDB-GENE-040426-811
- Name
- ribosomal protein SA
- Symbol
- rpsa Nomenclature History
- Previous Names
-
- laminin receptor 1 (ribosomal protein SA)
- lamr1 (1)
- zgc:55831
- zgc:77824
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal small subunit assembly. Predicted to be located in several cellular components, including nucleus; plasma membrane; and ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is expressed in eye. Orthologous to several human genes including RPSA (ribosomal protein SA).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55831 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| hi1479Tg | Transgenic insertion | Intron 1 | Unknown | DNA |
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No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Asplenia, isolated congenital | 271400 |
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Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018130 | Small ribosomal subunit protein uS2, conserved site |
| Domain | IPR032281 | Small ribosomal subunit protein uS2, C-terminal domain |
| Family | IPR001865 | Small ribosomal subunit protein uS2 |
| Family | IPR005707 | Small ribosomal subunit protein uS2, eukaryotic/archaeal |
| Family | IPR027498 | Small ribosomal subunit protein uS2, eukaryotic |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Small ribosomal subunit protein uS2 | Small ribosomal subunit protein uS2, conserved site | Small ribosomal subunit protein uS2, C-terminal domain | Small ribosomal subunit protein uS2, eukaryotic | Small ribosomal subunit protein uS2, eukaryotic/archaeal | Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily | Small ribosomal subunit protein uS2, vertebrates |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q803F6 | InterPro PDB | 308 | |||||||
| UniProtKB:B2GNT1 | InterPro | 308 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-146L13 | ZFIN Curated Data | |
| Contained in | BAC | CH211-215G15 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:55831 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:77824 | ||
| Encodes | cDNA | MGC:191259 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_201052 (1) | 1126 nt | ||
| Genomic | GenBank:CR925711 (2) | 200688 nt | ||
| Polypeptide | UniProtKB:B2GNT1 (1) | 308 aa |
- Xue, Y., Liu, D., Cui, G., Ding, Y., Ai, D., Gao, S., Zhang, Y., Suo, S., Wang, X., Lv, P., Zhou, C., Li, Y., Chen, X., Peng, G., Jing, N., Han, J.J., Liu, F. (2019) A 3D Atlas of Hematopoietic Stem and Progenitor Cell Expansion by Multi-dimensional RNA-Seq Analysis. Cell Reports. 27:1567-1578.e5
- He, W.X., Wu, M., Liu, Z., Li, Z., Wang, Y., Zhou, J., Yu, P., Zhang, X.J., Zhou, L., Gui, J.F. (2018) Oocyte-specific maternal Slbp2 is required for replication-dependent histone storage and early nuclear cleavage in zebrafish oogenesis and embryogenesis. RNA (New York, N.Y.). 24(12):1738-1748
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Chatzopoulou, A., Roy, U., Meijer, A.H., Alia, A., Spaink, H.P., Schaaf, M.J. (2015) Transcriptional and Metabolic Effects of Glucocorticoid Receptor α and β Signaling in Zebrafish. Endocrinology. 156(5):1757-69
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Wu, C.C., Tsai, T.H., Chang, C., Lee, T.T., Lin, C., Cheng, I.H., Sun, M.C., Chuang, Y.J., Chen, B.S. (2014) On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio. PLoS One. 9:e97902
- Carlson, P., Smalley, D.M., and Van Beneden, R.J. (2013) Proteomic analysis of arsenic-exposed zebrafish (Danio rerio) identifies altered expression in proteins involved in fibrosis and lipid uptake in a gender-specific manner. Toxicological sciences : an official journal of the Society of Toxicology. 134(1):83-91
- Ling, X.P., Lu, Y.H., and Huang, H.Q. (2012) Differential protein profile in zebrafish (Danio rerio) brain under the joint exposure of methyl parathion and cadmium. Environmental science and pollution research international. 19(9):3925-3941
- Lai, K., Amsterdam, A., Farrington, S., Bronson, R.T., Hopkins, N., and Lees, J.A. (2009) Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(1):76-85
- Lucitt, M.B., Price, T.S., Pizarro, A., Wu, W., Yocum, A.K., Seiler, C., Pack, M.A., Blair, I.A., Fitzgerald, G.A., and Grosser, T. (2008) Analysis of the zebrafish proteome during embryonic development. Molecular & cellular proteomics : MCP. 7(5):981-994
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