Gene

hspa4a

ID

ZDB-GENE-040426-2832

Name

heat shock protein 4a

Symbol

hspa4a Nomenclature History

Previous Names

hspa4l
wu:fc41d05
wu:fi59h02
wu:fj35c08
zgc:55506

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable adenyl-nucleotide exchange factor activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including gut; head; liver; pectoral fin bud; and somite. Human ortholog(s) of this gene implicated in Chagas disease. Orthologous to human HSPA4 (heat shock protein family A (Hsp70) member 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55506 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hspa4a Human Ortholog

No data available

Associated With hspa4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018181	Heat shock protein 70, conserved site
Family	IPR013126	Heat shock protein 70 family
Homologous_superfamily	IPR029047	Heat shock protein 70kD, peptide-binding domain superfamily
Homologous_superfamily	IPR029048	Heat shock protein 70kD, C-terminal domain superfamily
Homologous_superfamily	IPR043129	ATPase, nucleotide binding domain