Gene
klhdc3
- ID
- ZDB-GENE-040426-2426
- Name
- kelch domain containing 3
- Symbol
- klhdc3 Nomenclature History
- Previous Names
-
- zgc:85727 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable chromatin binding activity. Predicted to be active in cytoplasm. Orthologous to human KLHDC3 (kelch domain containing 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85727 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa10655 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 1 of 1
Show
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Kelch domain-containing protein 3-like | Kelch-type beta propeller |
|---|---|---|---|---|
| UniProtKB:A0A8M9QNZ4 | InterPro | 382 |
1 - 1 of 1
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
klhdc3-201
(1)
|
Ensembl | 681 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
- Nakajima, H., Ishikawa, H., Yamamoto, T., Chiba, A., Fukui, H., Sako, K., Fukumoto, M., Mattonet, K., Kwon, H.B., Hui, S.P., Dobreva, G.D., Kikuchi, K., Helker, C.S.M., Stainier, D.Y.R., Mochizuki, N. (2023) Endoderm-derived islet1-expressing cells differentiate into endothelial cells to function as the vascular HSPC niche in zebrafish. Developmental Cell. 58(3):224-238.e7
- Germano, G., Porazzi, P., Felix, C. (2022) Leukemia-associated transcription factor mllt3 is important for primitive erythroid development in zebrafish embryogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 251(10):1728-1740
- Mattonet, K., Riemslagh, F.W., Guenther, S., Prummel, K.D., Kesavan, G., Hans, S., Ebersberger, I., Brand, M., Burger, A., Reischauer, S., Mosimann, C., Stainier, D.Y.R. (2022) Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2. Science advances. 8:eabn2082
- Weaver, M.L., Piedade, W.P., Meshram, N.N., Famulski, J.K. (2020) Hyaloid vasculature and mmp2 activity play a role during optic fissure fusion in zebrafish. Scientific Reports. 10:10136
- Ghersi, J.J., Mahony, C.B., Bertrand, J.Y. (2019) bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish. Development (Cambridge, England). 146(6):
- Hong, S., Sahai-Hernandez, P., Chapla, D.G., Moremen, K.W., Traver, D., Wu, P. (2019) Direct Visualization of Live Zebrafish Glycan via Single-step Metabolic Labeling with Fluorophore-tagged Nucleotide Sugars. Angewandte Chemie (International ed. in English). 58(40):14327-14333
- Nelson, C.M., Lennon, V.A., Lee, H., Krug, R.G., Kamalova, A., Madigan, N.N., Clark, K.J., Windebank, A.J., Henley, J.R. (2019) Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord. Frontiers in cell and developmental biology. 7:56
- Posner, M., McDonald, M.S., Murray, K.L., Kiss, A.J. (2019) Why does the zebrafish cloche mutant develop lens cataract?. PLoS One. 14:e0211399
- Yang, Y.H.C., Kawakami, K., Stainier, D.Y. (2018) A new mode of pancreatic islet innervation revealed by live imaging in zebrafish. eLIFE. 7
- Hasegawa, T., Hall, C.J., Crosier, P.S., Abe, G., Kawakami, K., Kudo, A., Kawakami, A. (2017) Transient inflammatory response mediated by interleukin-1β is required for proper regeneration in zebrafish fin fold. eLIFE. 6
1 - 10 of 103
Show