ZFIN is now using GRCz12tu for Genomic Data
Gene
ralgps2
- ID
- ZDB-GENE-040426-1212
- Name
- Ral GEF with PH domain and SH3 binding motif 2
- Symbol
- ralgps2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of Ral protein signal transduction. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to human RALGPS2 (Ral GEF with PH domain and SH3 binding motif 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain |
| Family | IPR008937 | Ras-like guanine nucleotide exchange factor |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR023578 | Ras guanine nucleotide exchange factor domain superfamily |
| Homologous_superfamily | IPR036964 | Ras guanine-nucleotide exchange factor, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | PH-like domain superfamily | Pleckstrin homology domain | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Ras guanine nucleotide exchange factor domain superfamily | Ras guanine-nucleotide exchange factors catalytic domain | Ras-like guanine nucleotide exchange factor |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7SXZ6 | InterPro | 510 | ||||||
| UniProtKB:A0AB32TBT0 | InterPro | 568 | ||||||
| UniProtKB:A0A8M1PH81 | InterPro | 594 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ralgps2-201
(1)
|
Ensembl | 1,761 nt | ||
| mRNA |
ralgps2-202
(1)
|
Ensembl | 7,194 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers