Gene

eif4a1a

ID
ZDB-GENE-031030-2
Name
eukaryotic translation initiation factor 4A1A
Symbol
eif4a1a Nomenclature History
Previous Names
  • eif4a1
  • fb49a04
  • im:7143023 (1)
  • wu:fb20a10 (1)
  • wu:fb49a04 (1)
  • wu:fc76a02 (1)
  • wu:fc96c01 (1)
  • wu:fd15g03 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to act upstream of or within translational initiation. Is expressed in several structures, including immature eye; neural rod; neuromast; paraxial mesoderm; and somite. Orthologous to human EIF4A1 (eukaryotic translation initiation factor 4A1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
hi2596TgTransgenic insertionIntron 1UnknownDNA
la011382TgTransgenic insertionUnknownUnknownDNA
la016053TgTransgenic insertionUnknownUnknownDNA
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-eif4a1a
    (2)
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    Human Disease
    Associated With eif4a1a Human Ortholog
    No data available
    Associated With eif4a1a Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR001650 Helicase, C-terminal domain-like
    Domain IPR011545 DEAD/DEAH box helicase domain
    Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
    Domain IPR014014 RNA helicase, DEAD-box type, Q motif
    Domain IPR044728 ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain
    1 - 5 of 6 Show all
    Domain Details Per Protein
    Protein Additional Resources Length ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain DEAD/DEAH box helicase domain Helicase, C-terminal domain-like Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase RNA helicase, DEAD-box type, Q motif
    UniProtKB:Q802C9 InterPro 406
    1 - 1 of 1
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 7
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA eif4a1a-201 (1) Ensembl 2,370 nt
    ncRNA eif4a1a-002 (1) Ensembl 1,004 nt
    ncRNA eif4a1a-003 (1) Ensembl 677 nt
    ncRNA eif4a1a-004 (1) Ensembl 382 nt
    ncRNA eif4a1a-005 (1) Ensembl 883 nt
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    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanEIF4A117
    Amino acid sequence comparison (1)
    Conserved genome location (synteny) (3)
    MouseEif4a111
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    Citations
    1 - 10 of 13
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