Gene
pdca
- ID
- ZDB-GENE-031023-1
- Name
- phosducin a
- Symbol
- pdca Nomenclature History
- Previous Names
-
- pdc1
- pdcr
- PDCb1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within regulation of G protein-coupled receptor signaling pathway and visual perception. Predicted to be located in several cellular components, including cilium; cytosol; and photoreceptor inner segment. Predicted to be active in photoreceptor outer segment. Is expressed in eye and retina. Orthologous to human PDC (phosducin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Phosducin | Phosducin-like regulator | Phosducin, N-terminal domain superfamily | Phosducin, thioredoxin-like domain | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:F8W512 | InterPro | 236 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-147D18 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001291500 (1) | 2971 nt | ||
| Genomic | GenBank:CU570979 (1) | 93361 nt | ||
| Polypeptide | UniProtKB:F8W512 (1) | 236 aa |
- Mitchell, D.M., Sun, C., Hunter, S.S., New, D.D., Stenkamp, D.L. (2019) Regeneration associated transcriptional signature of retinal microglia and macrophages. Scientific Reports. 9:4768
- Sun, C., Galicia, C., Stenkamp, D.L. (2018) Transcripts within rod photoreceptors of the Zebrafish retina. BMC Genomics. 19:127
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Kassahn, K.S., Dang, V.T., Wilkins, S.J., Perkins, A.C., and Ragan, M.A. (2009) Evolution of gene function and regulatory control after whole-genome duplication: Comparative analyses in vertebrates. Genome research. 19(8):1404-1418
- Sato, Y., Hashiguchi, Y., and Nishida, M. (2009) Temporal pattern of loss/persistence of duplicate genes involved in signal transduction and metabolic pathways after teleost-specific genome duplication. BMC Evolutionary Biology. 9:127
- Toyama, R., Chen, X., Jhawar, N., Aamar, E., Epstein, J., Reany, N., Alon, S., Gothilf, Y., Klein, D.C., and Dawid, I.B. (2009) Transcriptome analysis of the zebrafish pineal gland. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(7):1813-1826
- Vihtelic, T.S., Fadool, J.M., Gao, J., Thornton, K.A., Hyde, D.R., and Wistow, G. (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Molecular Vision. 11:1083-1100
- Kobayashi, Y., Hisatomi, O., Yamamoto, S., and Tokunaga, F. (2002) Distribution of rod- and cone-specific phosducins in retinas of non-mammalian vertebrates. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 133(1):77-83
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