Gene

hspa9

ID
ZDB-GENE-030828-12
Name
heat shock protein 9
Symbol
hspa9 Nomenclature History
Previous Names
  • hspa9b (1)
  • cb740 (1)
  • crimsonless (1)
  • crs (1)
  • mortalin-2 (1)
  • wu:fc14d08
  • wu:fc27c10
  • wu:fc38a06
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Acts upstream of or within fin regeneration and hemopoiesis. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in several structures, including digestive system; eye; fin; midbrain; and segmental plate. Human ortholog(s) of this gene implicated in Parkinson's disease and autosomal dominant sideroblastic anemia 4. Orthologous to human HSPA9 (heat shock protein family A (Hsp70) member 9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
hi2473TgTransgenic insertionExon 1UnknownDNA
hi3366TgTransgenic insertionIntron 1UnknownDNA
hspa9_unspecifiedUnspecified AlleleUnknownUnknownnot specified
sa45508Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-hspa9N/A (2)
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Human Disease
Associated With hspa9 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant sideroblastic anemia 4 Alliance Anemia, sideroblastic, 4 182170
Even-plus syndrome 616854
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Associated With hspa9 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018181 Heat shock protein 70, conserved site
Family IPR012725 Chaperone DnaK
Family IPR013126 Heat shock protein 70 family
Homologous_superfamily IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily
Homologous_superfamily IPR029048 Heat shock protein 70kD, C-terminal domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length ATPase, nucleotide binding domain Chaperone DnaK Heat shock protein 70, conserved site Heat shock protein 70 family Heat shock protein 70kD, C-terminal domain superfamily Heat shock protein 70kD, peptide-binding domain superfamily
UniProtKB:Q5XJ12 InterPro 682
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 14
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hspa9-201 (1) Ensembl 4,421 nt
mRNA ottdart00000022285 (1) Havana 3,287 nt
ncRNA hspa9-002 (1) Ensembl 778 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanHSPA95
Phylogenetic tree (1)
Conserved genome location (synteny) (1)
Amino acid sequence comparison (4)
MouseHspa918
Conserved genome location (synteny) (1)
Amino acid sequence comparison (3)
Phylogenetic tree (1)
Citations
1 - 10 of 24
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