Gene

celf2

ID
ZDB-GENE-030826-35
Name
cugbp, Elav-like family member 2
Symbol
celf2 Nomenclature History
Previous Names
  • cb906 (1)
  • cugbp2
  • Etr-3 (1)
  • fj87b07
  • napor (1)
  • wu:fj87b07 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in mRNA splice site recognition and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within mRNA processing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including adaxial cell; immature eye; musculature system; nervous system; and neural plate. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 97. Orthologous to human CELF2 (CUGBP Elav-like family member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa2160Allele with one point mutationUnknownPremature StopENU
sa11849Allele with one point mutationUnknownSplice SiteENU
sa20283Allele with one point mutationUnknownSplice SiteENU
sa20284Allele with one point mutationUnknownPremature StopENU
sa26299Allele with one point mutationUnknownSplice SiteENU
sa30851Allele with one point mutationUnknownSplice SiteENU
sa33469Allele with one point mutationUnknownPremature StopENU
sa38441Allele with one point mutationUnknownUnknownENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With celf2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 97 Alliance Developmental and epileptic encephalopathy 97 619561
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Associated With celf2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR034196 CELF1/2, RNA recognition motif 1
Domain IPR034198 CELF1/2, RNA recognition motif 2
Domain IPR034199 CELF1/2, RNA recognition motif 3
Family IPR002343 Paraneoplastic encephalomyelitis antigen
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Domain Details Per Protein
Protein Additional Resources Length CELF1/2, RNA recognition motif 1 CELF1/2, RNA recognition motif 2 CELF1/2, RNA recognition motif 3 Nucleotide-binding alpha-beta plait domain superfamily Paraneoplastic encephalomyelitis antigen RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:A0A8M9Q097 InterPro 502
UniProtKB:A0A8M9QB14 InterPro 497
UniProtKB:A0A8M9Q087 InterPro 547
UniProtKB:A0A8M9QB04 InterPro 544
UniProtKB:A0A8M9PH22 InterPro 518
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 4
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA celf2-201 (1) Ensembl 1,699 nt
mRNA celf2-202 (1) Ensembl 1,886 nt
mRNA celf2-203 (1) Ensembl 1,545 nt
mRNA celf2-204 (1) Ensembl 3,045 nt
mRNA celf2-205 (1) Ensembl 1,538 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-198D18ZFIN Curated Data
EncodesESTcb906Thisse et al., 2001
EncodesESTfj87b07ZFIN Curated Data
EncodescDNAMGC:77203ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
HumanCELF210
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Phylogenetic tree (1)
MouseCelf22
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Phylogenetic tree (1)
Citations
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