Gene
opn1mw3
- ID
- ZDB-GENE-030728-6
- Name
- opsin 1 (cone pigments), medium-wave-sensitive, 3
- Symbol
- opn1mw3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and detection of light stimulus. Predicted to act upstream of or within signal transduction and visual perception. Predicted to be located in membrane. Predicted to be active in photoreceptor outer segment and plasma membrane. Is expressed in several structures, including endocrine system; gut; heart; integument; and visual system.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92290 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G-protein coupled receptor opsins | G protein-coupled receptor, rhodopsin-like | Opsin | Rhodopsin | Rhodopsin, N-terminal | Visual pigments (opsins) retinal binding site |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q8AYM7 | InterPro | 349 | |||||||
UniProtKB:A0A0N9NVT6 | InterPro | 349 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
opn1mw3-201
(1)
|
Ensembl | 1,379 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
---|---|---|---|---|---|
Tg(lcr.opn-opn1mw1:EGFP,opn1mw3:RFP) |
| 1 | Tsujimura et al., 2015 | ||
Tg(lcr.opn-opn1mw3:EGFP) |
|
| 1 | Tsujimura et al., 2015 | |
Tg(lcr.opn-opn1mw3:EGFP,opn1mw2:RFP) |
| 1 | Tsujimura et al., 2015 | ||
Tg(lcr.opn-opn1mw3:EGFP,opn1mw4:RFP) |
| 1 | Tsujimura et al., 2015 | ||
Tg(lcr.opn-opn1mw4:EGFP,opn1mw3:RFP) |
| 1 | Tsujimura et al., 2015 | ||
Tg(opn1mw3:EGFP) |
|
| 1 | (3) | |
TgPAC(lcr.opn-opn1mw3:GFP,opn1mw4:RFP) |
| 1 | Tsujimura et al., 2015 | ||
TgPAC(opn1mw2:GFP-opn1mw3-lcr.opn) |
| 1 | Tsujimura et al., 2015 | ||
TgPAC(opn1mw3:GFP-lcr.opn) |
|
| 1 | Tsujimura et al., 2015 |
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Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-263A23 | ||
Encodes | cDNA | MGC:92290 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_182892 (1) | 1424 nt | ||
Genomic | GenBank:AL732567 (1) | 152840 nt | ||
Polypeptide | UniProtKB:A0A0N9NVT6 (1) | 349 aa |
No data available
- Hu, H., Qin, Y., Qu, Z., Huang, Y., Ren, X., Liu, M., Liu, F., Gao, P. (2024) The Zpr-3 Antibody Recognizes the 320-354 Region of Rho and Labels Both Rods and Green Cones in Zebrafish. Zebrafish. 21(6):394-400
- Angueyra, J.M., Kunze, V.P., Patak, L.K., Kim, H., Kindt, K., Li, W. (2023) Transcription factors underlying photoreceptor diversity. eLIFE. 12:
- Lu, K., Liang, X.F., Tang, S.L., Wu, J., Zhang, L., Wang, Y., Chai, F. (2023) Role of short-wave-sensitive 1 (sws1) in cone development and first feeding in larval zebrafish. Fish physiology and biochemistry. 49(5):801-813
- Ulhaq, Z.S., Ogino, Y., Tse, W.K.F. (2023) Deciphering the pathogenesis of retinopathy associated with carnitine palmitoyltransferase I deficiency in zebrafish model. Biochemical and Biophysical Research Communications. 664:100107100-107
- Zhang, J., Jing, M., Li, P., Sun, L., Pi, X., Jiang, N., Zhu, K.K., Li, H., Li, J., Wang, M., Zhang, J., Liu, M., Mu, H., Hu, Y., Cui, X. (2023) Knockout of DLIC1 leads to retinal cone degeneration via disturbing Rab8 transport in zebrafish. Biochimica et biophysica acta. Molecular basis of disease. 1869(4):166645
- Liu, F., Qin, Y., Huang, Y., Gao, P., Li, J., Yu, S., Jia, D., Chen, X., Lv, Y., Tu, J., Sun, K., Han, Y., Reilly, J., Shu, X., Lu, Q., Tang, Z., Xu, C., Luo, D., Liu, M. (2022) Rod genesis driven by mafba in an nrl knockout zebrafish model with altered photoreceptor composition and progressive retinal degeneration. PLoS Genetics. 18:e1009841
- Liang, Q., Afriyie, G., Chen, Z., Xu, Z., Dong, Z., Wang, Z., Guo, Y. (2021) Analysis of Opsin Gene Family of Crimson Snapper (Lutjanus erythropterus). Gene. 807:145960
- Mackin, R.D., Frey, R.A., Gutierrez, C., Farre, A.A., Kawamura, S., Mitchell, D.M., Stenkamp, D.L. (2019) Endocrine regulation of multichromatic color vision. Proceedings of the National Academy of Sciences of the United States of America. 116(34):16882-16891
- Ogawa, Y., Shiraki, T., Asano, Y., Muto, A., Kawakami, K., Suzuki, Y., Kojima, D., Fukada, Y. (2019) Six6 and Six7 coordinately regulate expression of middle-wavelength opsins in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 116(10):4651-4660
- Shi, Q., Wang, Z., Chen, L., Fu, J., Han, J., Hu, B., Zhou, B. (2019) Optical toxicity of triphenyl phosphate in zebrafish larvae. Aquatic toxicology (Amsterdam, Netherlands). 210:139-147
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