Gene

anxa11b

ID

ZDB-GENE-030707-5

Name

annexin A11b

Symbol

anxa11b Nomenclature History

Previous Names

cb755 (1)
hm:zeh0376
zeh0376

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to enable calcium-dependent phospholipid binding activity and phosphatidylserine binding activity. Predicted to be involved in cytokinetic process and phagocytosis. Predicted to be active in several cellular components, including nucleus; plasma membrane; and vesicle membrane. Is expressed in several structures, including cardiovascular system; digestive system; immature eye; integument; and sensory system. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 23 and inclusion body myopathy and brain white matter abnormalities. Orthologous to human ANXA11 (annexin A11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb755 (46 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With anxa11b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
amyotrophic lateral sclerosis type 23	Alliance	Amyotrophic lateral sclerosis 23	617839
inclusion body myopathy and brain white matter abnormalities	Alliance	Inclusion body myopathy and brain white matter abnormalities	619733

Associated With anxa11b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018252	Annexin repeat, conserved site
Family	IPR001464	Annexin
Homologous_superfamily	IPR037104	Annexin superfamily
Repeat	IPR018502	Annexin repeat

Domain Details Per Protein

Protein	Additional Resources	Length	Annexin	Annexin repeat	Annexin repeat, conserved site	Annexin superfamily
UniProtKB:Q804G3	InterPro	485
UniProtKB:A0A8M1PC84	InterPro	485

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	anxa11b-201 (1) Ensembl	Ensembl	2,835 nt	Select Tool ZFIN BLAST
ncRNA	anxa11b-002 (1) Ensembl	Ensembl	771 nt	Select Tool ZFIN BLAST
ncRNA	anxa11b-003 (1) Ensembl	Ensembl	117 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations